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Hydrocodone  


Hydrocodone is an effective antitussive (anti-cough) agent, and as an opiate it is also an effective analgesic for mild to moderate pain control. Five mg of hydrocodone is equivalent to 30 mg of codeine when administered orally. Early comparisons concluded that hydrocodone and morphine were equipotent for pain control in humans. However, it is now considered that a dose of 15 mg (1/4 gr) of hydrocodone is equivalent to 10 mg (1/6 gr) of morphine. Hydrocodone is considered to be morphine-like in all respects.

There are over 200 products containing hydrocodone in the U.S. In its most usual product forms hydrocodone is combined with acetaminophen (Vicodin, Lortab), but it is also combined with aspirin (Lortab ASA), ibuprofen (Vicoprofen), and antihistamines (Hycomine). Both tablet and liquid forms of hydrocodone are available (e.g., Tussionex)

Hydrocodone is in Schedule II of the Controlled Substances Act. Preparations containing hydrocodone in combination with other non-narcotic medicinal ingredients are in Schedule III.

Vicodin, hydrocodone in combination with acetaminophen, is a commonly abused version of hydrocodone. Vicodin, as with all narcotic analgesics, can be habit forming---causing dependence, tolerance, and withdrawal symptoms if not used as it is prescribed. Even when used as prescribed, the following effects are possible:

COMMON SIDE EFFECTS MAY INCLUDE: dizziness, light-headedness, nausea, sedation, vomiting, and constipation.

LESS COMMON SIDE EFFECTS:
allergic reactions, blood disorders, mood changes, mental cloudiness, anxiety, lethargy, urine retention, ureteral spasm, irregular breathing, respiratory depression, and skin rash.

SYMPTOMS OF OVERDOSE: bluish tinge to skin, cold and clammy skin, extreme sleepiness progressing to a possible state of unresponsiveness or coma, heart problems, heavy perspiration, kidney problems, limp muscles, liver failure, low blood pressure, nausea, slow heartbeat, troubled or slowed breathing, and vomiting.

 


Narcotics

Prescription Drugs

In 1998 there were over 56 million new prescriptions written for hydrocodone products and by 2000 there were over 89 million. From 1990 the average consumption nationwide has increased by 300%. In the same period there has been a 500% increase in the number of Emergency Department visits attributed to hydrocodone abuse with 19,221 visits estimated in 2000. in 2001, that number jumped to 21,567. In the first half of 2002 (estimates from Jan.-June), the number of ED mentions was 12, 033.

Source: DEA Diversion Control Program, Hydrocodone, Aug. 2001

Currently, about 20 tons of hydrocodone products are used annually in the United States.

Source: DEA



 


Oxycodone, Hydrocodone and Polydrug Use, 2002 (The DAWN Report, July 2004)

Treatment Admissions Involving Narcotic Painkillers: 2002 Update (The DASIS Report, July 23, 2004)

Nonmedical Use of Prescription Pain Relievers: The NSDUH Report
(May 21, 2004)

 

 


Nonmedical Use of Prescription-Type Drugs among Youths and Young Adults:

The NHSDA Report, January 16, 2003

Trouble in the Medicine Chest (I):
CSAP Prevention Alert, Vol 6 No 4, 3/7/03

Trouble in the Medicine Chest (II):
CSAP Prevention Alert, Vol 6 No 5, 3/28/03