Thebaine, a minor content of opium, is controlled in Schedule II of the Controlled Substance Act as well as under international law. Although chemically similar to both morphine and codeine, this drug produces stimulant rather than depressant effects. This drug is not used therapeutically, but is converted into a variety of substances including oxycodone, oxymorphone, nalbuphine, naloxone, naltrexone, and buprenorphine. The United States ranks first in the world in utilization.
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